The Copa AUF Uruguay, contested since 2022, is the nationwide main cup and brings together clubs affiliated with the AUF and the Organización del Fútbol del Interior.
| Season | Uruguayan Cup winner | Runner-up | Trophy |
|---|---|---|---|
| 2026 | - | - The 2026 Copa AUF Uruguay is in progress and no champion has been determined yet. | — |
| 2025 | CA Peñarol | Plaza Colonia Final on October 29, 2025: 2-0. |  |
| 2024 | Defensor Sporting | Club Nacional Final on December 6, 2024: 2-2; Defensor Sporting won 3-1 on penalties. | |
| 2023 | Defensor Sporting | Montevideo City Torque The 2023 edition’s final was played on May 22, 2024: 2-2; Defensor Sporting won 4-2 on penalties. | |
| 2022 | Defensor Sporting | La Luz FC Final on November 13, 2022: 1-0. | |
